The Marsico Lung Institute (MLI)/CF Research and Treatment Center at the University of North Carolina at Chapel Hill (UNC)
Mentor: Richard C. Boucher
Dr Ehre received her PhD in pathophysiology from Université Pierre et Marie Curie in Paris, France; a joint initiative with UNC. She then completed postdoctoral fellow training and a research associate position at the same university. Dr Ehre is currently Assistant Professor of Pediatrics within the Marsico Lung Institute at UNC. Her laboratory specializes in the biophysical and biochemical properties of mucus, which are affected in various airway diseases, such as CF. The studies conducted in her laboratory utilize cell culture, human, and small animal models, and include the testing of new pharmacological reagents aimed at improving mucous clearance in the lungs.
University of Washington, Seattle
Mentor: Pradeep Singh
Dr Hisert received her PhD from Rockefeller University in 2004 and her MD from Weill Cornell in 2006. After residency in Internal Medicine at Columbia University Medical Center, she joined the University of Washington (UW) to pursue a fellowship in Pulmonary and Critical Care Medicine. At UW, Dr Hisert focused her clinical work and research on cystic fibrosis. She sees patients in the Adult Cystic Fibrosis clinic, and performs basic and translational research to understand the role of monocytes and macrophages in CF inflammation. Under the mentorship of Drs Pradeep Singh, Anne Manicone, and Lev Becker, Dr Hisert is investigating how inflammation may add to CF pathology, how CF airway stimuli alter macrophage phenotypes, and how CFTR deficiency impairs monocyte and macrophage functions.
McGill University, Montreal, Canada
Mentor: John W. Hanrahan
Dr Nguyen has clinical expertise in adult pulmonary medicine and research expertise in CF molecular microbiology, bacterial genetics, and host-pathogen interactions. After postdoctoral fellow training with Dr Jane Burns and Dr Pradeep Singh at the University of Washington, she is now an Assistant Professor in the Department of Medicine at McGill University. Her research is focused on Pseudomonas molecular microbiology, host-pathogen interactions and, inflammation in chronic CF lung disease.
Robert A. Quinn
University of California, San Diego
Mentor: Pieter Dorrestein
Dr Quinn’s PhD dissertation on the microbial communities of epizootic shell disease in the American lobster sparked his interest in polymicrobial infections, and this led to an interest in CF. He received a postdoctoral fellowship from Cystic Fibrosis Research Inc. on a proposal to identify metagenomic biomarkers of CF respiratory exacerbations with the world-renowned microbial ecologist Professor Forest Rohwer. Early findings led him to investigate the chemistry of the CF lung with metabolomics. Here, he began a collaboration with Dr Pieter Dorrestein at UCSD, a world leader in this burgeoning field.